I've posted photos of my home office / anime-haven before, but it's been awhile. The following photos are the most recent, taken about a year ago (before Rowan was born). Since then, in order to put in Rowan's crib and changing table, I have moved some things around and removed the guest bed. (Rowan still gets to enjoy the posters, though.) Except for select titles that I like to have close by, I keep my modest anime and manga collection in other rooms (such as the living room where my TV and PS2 reside). Naturally, since these photos are over a year old and I don't typically throw things away, I have more stuff now.
Update 07/10/09: I recently started a group on Flickr to highlight people's Otaku Rooms. I hope you'll check it out and share your photos!